I am shooting at the highest resolution and the “fine” setting, so as far as I know, nothing else can be changed. When I open the pics on my computer they are not at clear as i would like them to be. Up to an 8×10 is pretty good but anything over that is not so hot. I used to have a cheapo digital camera that would give me great detail such as the pores on someones face even when zooming in 4-5 times on the computer. I know a lady that owns a Canon EOS 5d and her photos are AMAZING. She also shoots with 50mm lens. I am thinking of trading my Nikon for the Canon 5d but I am wondering if i am making a mistake? I realize that her camera and my camera are not the same in megapixels or price but is it really worth the money to upgrade? I also own a sb-600 flash and my lens is a NIkkor lens…. Does this mean that if i trade for a Canon that my accesories will not work or fit? I need help deciding… If my accessories will be useless on a canon camera, should i trade for a Nikon camera that is similar to the Canon 5d? What Nikon camera is the equivelent? I really love the clarity, brightness, no noise, and brilliance of the photos that my friend gets with her 5d. I am an amateur photographer but hoping to someday move up in the world – you can see some of my work here. Http://www.flutterbynight84.deviantart.com ———– any help?
Wow, a 1.8/50? It can't be the glass since I've heard a lot of good things about Nikon's "nifty fifty" (unless the glass does not appear clear). Is this an older model?
Have you tried running it on manual just to test if the sharpness is off? If it isn't, then maybe your autofocus is screwy and needs to go back to the manufacturer.
If it's because you're running manual, then you could look for a magnifier for the viewfinder that might make it easier for you to tell details.
It sounds like you're shooting JPEG as well. Have you tried RAW? Is the ISO low? Are you shooting really wide aperture and have you tried stepping down to F/2 or smaller just to see if it's the fineness of your field of depth that's contributing to your results?
As you can see, there's a lot that could be going wrong here. Even the way you hold the camera could contribute to fuzzy shots.
If all of this was tried and failed, then maybe the camera just doesn't feel right. I wouldn't suggest immediately going to Canon, but I WOULD suggest going to the camera shop and asking if you can test-feel the other models.
Also, not to nudge (okay, maybe I am nudging), but Pentax has a good variety of portraiture-length lenses that might be worth looking into if you really want to switch.

Are you using a good quality lens? If I’m thinking of the right lens, I am guessing the one you are using is a lens that’s very good quality for it’s price, but it’s also a very cheap lens.
You should check with your friend about what lens they are using. If she’s using the 50mm 1.2 L series (~1500$) then that might be part of it too.
To answer your other question,Your flash will work, but your lens will not fit on a 5d.
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